Oppositinines A and B: new vasorelaxant beta-carboline alkaloids from Neisosperma oppositifolia.
نویسندگان
چکیده
A phytochemical study on the bark of Neisosperma oppositifolia (Apocynaceae) yielded two new beta-carboline indole alkaloids, oppositinines A (1) and B (2), together with five known alkaloids, isoreserpiline, isocarapanaubine, vobasine, 10-methoxydihydrocorynantheol-N-oxide, and ochropposinine oxindole. Structural elucidation of 1 and 2 was performed using 2D NMR methods. Oppositinines A (1) and B (2) showed potent vasorelaxant effects on the rat aorta.
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 58 8 شماره
صفحات -
تاریخ انتشار 2010